Cri du chat syndrome (aka chromosome 5p deletion syndrome, Lejeune's syndrome, from French meaning "cat cry") is a rare genetic disorder, due to a deletion from chromosome 5.
Sx
Characteristic cat-like cry, similar to that of a meowing kitten, due to problems w/ larynx and nervous system. 33% of kids lose the cry by 2yo
Feeding problems because of difficulty swallowing and sucking
Low birth weight and poor growth
Severe cognitive, speech, and motor delays
behavioral problems, e.g. hyperactivity, aggression, tantrums, repetitive movements
Unusual facial features which may change over time
Excessive drooling
Small head and jaw
Wide eyes
Skin tags in front of eyes
Hypotonia
Microecaphy
Growth retardation
Round face with full cheeks
Hypertelorism
Epicanthal folds
Down-slanting palpebral fissures
Strabismus
Flat nasal bridge
Down-turned mouth
Micrognathia
Low-set ears
Short fingers
Single palmar creases
Cardiac defects, e.g. VSD (ventricular septal defect), ASD (atrial septal defect), PDA (patent ductus arteriosus), tetralogy of Fallot
Medicinenet.com Word of the Day Medicinenet.com Daily News
Medpage Today Latest Medical News
Health.com Happy & Healthy
Medical News Today headlines
Internal Medicine Clinical News
Modern Medicine News Modern Medicine Feature articles
Cleveland Clinic Journal of Medicine
BMJ Latest news BMJ Latest research BMJ Education
JAMA Current issue
The Lancet Current issue
NEJM Current issue
ScienceMag Current issue
NIH PubMed Health Featured reviews
ABC Health news ABC Health & Wellbeing ABC Health Minutes ABC RN's The Health Report ABC All in The Mind
BBC News - Health (International)
NSW Health Minister for Health Minister for Mental Health NSW Health Publications AI of Health & Welfare Publications Department of Health Publications
WHO Health news WHO Emergencies, disasters news WHO Disease Outbreaks WHO Health feature stories