Adrenaline (aka epinephrine) is drug used for numerous conditions.

• Anaphylaxis
• Cardiac arrest
• Superficial bleeding
• Croup, when it is inhaled
• Asthma, when other Tx not effective

• Can be given IV, IM, inhalation, or injection just under the skin
• Normally produced by both the adrenal glands, and certain neurons
• Plays important role in the fight-or-flight response by increasing blood flow to muscles, output to the heart, pupil dilation, and blood sugar
• It does this by its effects on alpha and beta receptors

• Shakiness
• Anxiety
• Sweating
• Fast HR, occasionally
• HTN, occasionally
• Cardiac arrhythmia, occasionally
• Safety of its use during pregnancy and breastfeeding is unclear, but the benefits to the mother must be considered

• The Japanese chemist Jokichi Takamine 1st isolated it in 1901
• Wholesale cost is between $0.10-0.95 USD a vial
• An autoinjector for anaphylaxis with epinephrine, costs about $600USD