Choluria is the presence of bile in urine.

• Dark or brown urine, often referred to as the color of Coca-Cola

• Usually manifested when serum bilirubin >1.5mg/dL
• Presence of chlouria is useful Sx to distinguish, if a patient presents with jaundice has either:
  • Liver disease (direct hyperbilirubinemia), which is due to excess conjugated (direct) bilirubin in blood, which is eliinaetd by kidneys
  • Hemolysis (indirect hyperbilirubinemia), involving unconjugted (indirect) bilirubin which is bound to albumin, and thus not eliminated in urine

• Common Sx of liver diseases, e.g. hepatitis and cirrhosis